Independiente vs San Lorenzo Prediction, Betting Tips, Lineups & Odds | 21 Sep 2025

Primera División Betting Preview: Independiente vs San Lorenzo

Independiente host San Lorenzo in this Argentine Primera División meeting, with kick-off set for 01:30 on Monday 22 September. Our betting preview features expert predictions, betting tips, the latest odds, H2H stats, team news and both predicted and confirmed lineups.

We Predict a Close Encounter

San Lorenzo with a +0.5 goal start at 1.80 looks like a confident play. The visitors should be able to triumph or draw against Independiente, with this Asian Handicap pick looking an attractive option and we expect the line to be covered.

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Independiente Won When They Last Played San Lorenzo

Independiente lost their last game, being beaten 1-0 at home to Banfield. Julio Vaccari's team dominated possession with 68% of the ball and had two shots on target.

San Lorenzo have lost consecutive Primera División away games. Recently, they suffered a 2-0 defeat against Racing Club. El Ciclón had 49% possession, but were unable to record a shot on goal.

Head-to-Head Statistics

Independiente have not lost to San Lorenzo in the past seven meetings. In their last encounter, it was a 2-1 away victory for Independiente. The previous 7 H2H games have gone the way of Independiente two times along with five draws.

Primera División		G	W	D	L	GF	GA	GD	GD	P
5	Independiente	16	8	5	3	23	12	11	23:12	29
9	San Lorenzo	16	7	6	3	14	10	4	14:10	27

View Full Table

2 wins, 5 losses and 3 draws, averaging 1.1 goals from 3.7 shots on goal and 8.7 attempts. Independiente have had 59.8% possession and 4.4 corners per match. On average, the opposition have scored 1.4 goals from 3.2 shots on goal and 6.7 attempts, while being awarded 5.6 corners.

Top goalscorer Felipe Loyola has found the net 2 times, with Nicolas Freire, Gabriel Avalos, Alvaro Angulo and Santiago Gabriel Montiel scoring 1 each. Santiago Gabriel Montiel, Leonardo Godoy and Federico Mancuello are the leading assists makers with 1.

San Lorenzo de Almagro have 4 victories, 3 defeats and 3 draws, with an average of 1.4 goals from 6.7 attempts and 2.3 shots on goal. There’s been an average of 41.2% possession, 4.3 corners awarded and 3.2 corners against them, while they’ve conceded 1.4 goals from 5.0 attempts and 1.9 shots on goal.

Alexis Cuello has top scored with 2, while Branco Salinardi, Elias Baez and Andres Vombergar are next on 1. Elias Baez, Matias Reali and Ezequiel Cerutti have managed 1 assists in the last 10 games.

Predicted & Confirmed Lineups

Independiente predicted lineup (4-2-3-1): Rodrigo Rey (GK), Federico Vera, Kevin Lomonaco, Sebastián Valdéz, Facundo Zabala, Felipe Loyola, Ivan Marcone, Walter Mazzantti, Lautaro Millan, Santiago Montiel, Ignacio Pussetto.

San Lorenzo predicted lineup (4-3-3): Orlando Gill (GK), Fabricio López, Jhohan Romaña, Daniel Herrera, Elias Baez, Nicolás Tripichio, Ignacio Perruzzi, Juan Rattalino, Ezequiel Cerutti, Andrés Vombergar, Alexis Cuello.

Independiente vs San Lorenzo Prediction & Betting Tips

Our Independiente vs San Lorenzo betting tips provide expert coverage of all major angles, including our main match prediction, top player prop picks, correct score recommendation, corners betting angle and best bet builder insights.

Match Prediction

San Lorenzo +0.5 are capable of landing a return for this Primera División encounter. We’ll take them on the Asian Handicap, with the latest stats backing up this pick which is priced at odds of 1.80.

It's important to understand the players who are unavailable for the upcoming Primera División action and the respective form of each team. If you want stats, you have come to the right place and they form the basis of our football predictions.

Key Independiente vs San Lorenzo league stats:

• The +0.5 line has been covered by San Lorenzo in 15 of their last 20 games.
• The +0.5 line has been covered by San Lorenzo in 7 of their last 10 games.
• The -0.5 line hasn’t been covered by Independiente in 8 consecutive games.
• The -0.5 line hasn’t been covered by Independiente in 14 of their last 20 games.
• The -0.5 line hasn’t been covered by Independiente in 5 of their last 7 games against San Lorenzo.

San Lorenzo +0.5 Probability

According to the best betting sites, our pick has a 55.6% chance of landing a return. After careful examination, our experts calculate this probability to be somewhere between 60-65%. This is why we regard this as a value bet.

We advise that you move the line if you are looking for a larger price about the same selection. Make your prediction and land the bigger odds from your wager as a result.

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Our Match Prediction

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Correct Score Prediction

Independiente 1 - 1 San Lorenzo

We’ve got a correct score prediction which involves the teams playing out a 1-1 draw. Odds of 6.25 look appealing and we should get a run for our money here.

Player Prop Picks

Corners Prediction

Independiente Under 5.5 Corners 

Independiente have had under 5.5 corners in three consecutive home matches, with San Lorenzo conceding under 5.5 corners in the previous five games. It looks a logical viewpoint that the Team Corners line won’t be reached and you can land a price of 1.62 for this Independiente wager.

League Games

League Games

Last 10 Total For Against

Last 10 at Home Total For Against

Last 10 Away Total For Against

Independiente

Total

10.00 4.40 5.60

Home

9.00 5.40 3.60

Away

8.40 3.90 4.50

San Lorenzo

Total

7.50 4.30 3.20

Home

7.90 4.40 3.50

Away

7.70 4.40 3.30

Latest Corner Odds

Total Corners

Independiente Corners

San Lorenzo Corners

Most Corners

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Independiente vs San Lorenzo Odds

The odds are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

Bookies Have Independiente as Favourites

The Independiente betting odds are 2.02 which means that they’re favourites to land victory in this Primera División encounter. It’s also suggested by the bookies that this team have a 50% chance of winning. If you want to wager on the underdog, San Lorenzo have been priced up at 4.30.

Independiente can be backed at 2.85 on the Half-Time Result and you’ll need them to have their noses in front by the break. San Lorenzo can be chanced at 4.90 and the draw is 1.84.

Under 2.5 Goals is currently the betting favourite and a bet on this option would mean you need no more than two goals to be scored. Providing that at least one side fails to score, then the No pick on the Both Teams to Score market will be a winner at 1.43.

The best football betting sites will provide a first-class service and that includes getting hundreds of markets. Scan through them for any Primera División game and take your pick.

Gabriel Ávalos is the First Goalscorer Favourite

There’s the chance to back Gabriel Ávalos at 5.50 to be the First Goalscorer, with the favourite on this market available at similar odds to find the net last.

Independiente vs San Lorenzo Lineups & Team News

Always review the Independiente vs San Lorenzo team news before locking in your bets. We’ll have the predicted and confirmed Primera División lineups for you plus all the latest on player injuries.

Independiente Team Page San Lorenzo Team Page