West Virginia vs Kansas Prediction, Picks & Odds | 20 Sep 2025

College Football Betting Preview: West Virginia vs Kansas

West Virginia go up against Kansas in this NCAAF Week 4 matchup at David Booth Kansas Memorial Stadium, with kickoff scheduled for 06:00 on Sunday 21 September. Our betting preview features expert predictions, picks, the latest betting odds and H2H stats.

Kansas to Outclass West Virginia

We have decided to go for Kansas against the spread in order to get the best value. They should be able to cover the -12.5 line at odds of 1.87 when they take on West Virginia.

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4 Wins in Previous 5 H2H Games for West Virginia

West Virginia Mountaineers won their previous game, beating Pittsburgh Panthers at home. It was a 31-24 win at Mountaineer Field. 

Kansas Jayhawks have secured back-to-back home victories. Their last game was on the road and a 42-31 loss occurred against Missouri Tigers at Faurot Field.

Head-to-Head Statistics

The last matchup between West Virginia and Kansas saw the former win. It was a 32-28 scoreline at Mountaineer Field. The past 5 H2H games have seen West Virginia land four wins.

Quarterbacks

Nicco Marchiol

Jalon Daniels

West Virginia vs Kansas Prediction & Picks

Get fully prepped for West Virginia vs Kansas with our betting guide, featuring our expert match pick, predicted scoreline, top player props and a value-focused bet builder.

Game Prediction

Let’s go for the favorites at a generous -12.5 on the spread. We can get odds of 1.87 that Kansas win this college football showdown by a big margin.

Team news plays a key role in our college football forecasts and we’re always tracking players with injury concerns. We also stay on top of the form guide, supported by detailed stats that help paint a clearer picture of what to expect

Key West Virginia vs Kansas stats:

• The -12.5 line has been covered by Kansas in 4 of their last 5 games at home.
• The -12.5 line has been covered by Kansas in 3 consecutive games at home.

Kansas -12.5 Probability

According to the latest betting odds, our pick has a 53.5% chance of winning. Taking all factors into consideration, our cappers think there’s a stronger chance of success and estimate the probability to be closer to 60%. This college bet can therefore be backed with confidence.

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Best Bet

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Player Prop Picks

Correct Score Prediction

West Virginia 21 - 42 Kansas

Should you want a wager that can land a big return, then look no further than the correct score lines. Bet on the Jayhawks to win 42-21 and leverage a massive payout if this happens.

West Virginia vs Kansas Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.

Kansas Big Favorites With the Books

Kansas are strong 1.20 favorites to win this college game according to the Moneyline betting odds. The sportsbooks give them a 83% chance of claiming victory. West Virginia are regarded as a long shot to win and you can currently back them at 4.65.

The current spread is 12.5 and total points is 54.5. The beauty of the Totals is that you only have to choose from one of two options. If you fancy Under 54.5, then the odds are 1.91.

If you’re wagering on college football, we recommend heading to the best betting sites and scanning through the huge selection of team props and game lines. There’s the opportunity to bet pre-game and in-game.

Daniel Hishaw Jr. Favorite to Be First TD Scorer

Daniel Hishaw Jr. is the First Touchdown Scorer favorite at 6.00. Alternatively, there’s the opportunity to simply back him to score a TD anytime at 1.61.

Touchdown

Receiving Yards

Rushing Yards

Passing Yards

Micro Betting

For those looking to enjoy a thrilling in-game wager, then college football micro betting could be up your street. You are now able to wager on what will happen on the next snap by staking your money on the Next Play Result.

Kansas Looking to Extend Strong Home Form

Kansas have put together five wins in a row at David Booth Kansas Memorial Stadium. They own a 6-4 mark in their past 10 home games, averaging 33.60 points on offense and surrendering 19.60 on defense.

West Virginia have a 5-5 record in their last 10 games on the road, averaging 29.30 points scored and 33.00 points allowed.

In their most recent matchup at David Booth Kansas Memorial Stadium, West Virginia got the better of Kansas 34-28.

Last 10 Games		W-L	P	PF	PA	O54.5	U54.5
Kansas Home Stats		6-4	53.20	33.60	19.60	5	5
West Virginia Away Stats		5-5	62.30	29.30	33.00	8	2

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O54.5 = Games Over 54.5 Points
• U54.5 = Games Under 54.5 Points

Last 5 & H2H

Latest regular season and playoff games stats.

West Virginia Mountaineers Stats

Kansas Jayhawks Stats

Moneyline

• 5 wins and 5 defeats in the last 10 games
• 5 wins and 5 defeats in the last 10 games on the road

Moneyline

• 6 wins and 4 defeats in the last 10 games
• 6 wins and 4 defeats in the last 10 home games

Point Spread

• +12.5 Betting Line: Have covered the spread in 7 of the last 10 games
• +12.5 Betting Line on the Road: Have covered the spread in 8 of the last 10 games on the road

Point Spread

• -12.5 Betting Line: Have covered the spread in 4 of the last 10 games
• -12.5 Betting Line at Home: Have covered the spread in 5 of the last 10 home games

Total Points

• Game Totals: An average of 58.70 pts in the previous 10 games
• Game Totals on the Road: An average of 62.30 pts in the previous 10 games on the road
• Over 54.5: Covered in 7 of the previous 10 games
• Over 54.5 on the Road: Covered in 8 of the previous 10 games on the road
• Team Totals: Have scored an average of 28.40 pts and allowed 30.30 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 29.30 pts and allowed 33.00 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 57.30 pts in the previous 10 games
• Game Totals at Home: An average of 53.20 pts in the previous 10 home games
• Over 54.5: Covered in 7 of the previous 10 games
• Over 54.5 at Home: Covered in 5 of the previous 10 home games
• Team Totals: Have scored an average of 32.40 pts and allowed 24.90 pts in the last 10 games
• Team Totals at Home: Have scored an average of 33.60 pts and allowed 19.60 pts in the last 10 home games

NCAAF Standings Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Big 12	W	L	PF	PA	N. Pts	Home	Away	Strk
Arizona	3	0	111	26	85	3-0	0-0	3W
BYU	2	0	96	3	93	2-0	0-0	2W
Houston	3	0	98	29	69	2-0	1-0	3W
Iowa State	4	0	119	57	62	2-0	2-0	4W
TCU	3	0	125	59	66	2-0	1-0	3W
Texas Tech	4	0	208	45	163	3-0	1-0	4W
UCF	2	0	85	17	68	2-0	0-0	2W
Utah	3	1	147	59	88	1-1	2-0	1L
Baylor	2	1	114	90	24	1-1	1-0	2W
Cincinnati	2	1	121	40	81	2-1	0-0	2W
Kansas	2	1	108	56	52	2-0	0-1	1L
West Virginia	2	1	86	44	42	2-0	0-1	1W
Colorado	1	2	71	70	1	1-1	0-1	1L
Oklahoma State	1	2	42	95	-53	1-1	0-1	2L
Kansas State	1	3	97	106	-9	1-2	0-1	2L